Weigh and powder 20 tablets. Shake a quantity
of the powder containing 0.2 g of Furosemide with 300 mL of 0.1M sodium
hydroxide for 10 minutes, add sufficient 0.1M sodium hydroxide to produce 500
mL and filter. Dilute 5 mL to 250 mL with 0.1M sodium hydroxide and measure the
absorbance of the resulting solution at the maximum at 271 nm. Calculate the
content of C12H11ClN2O5S taking 580
as the value of A (1%, 1 cm) at the maximum at 271 nm.
.
Mg/tablet =
Spl reading x 1000 x 500___
x 250 x Average weight
580 100
Spl. Wt. 5
(mg)
(mg)
Mg/tablet x100
% =-----------------------
Labeled Claim
